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Organic Synthesis, the Disconnection Approach by Stuart Warren,

This book will help students to design their own organic synthesis, giving a wide coverage of synthetic methods. The disconnection approach is used throughout so that starting materials are chosen after analysing the structure of the target molecule. There are forty chapters: those on the synthesis of given types of molecule alternate with strategy chapters in which the methods just learnt are placed in a wider context. The instructional chapters cover many ways of making each type of molecule starting with simple aromatic organ works and aliphatic compounds with one functional group organ works and progressing to molecules with many functional groups. The number organ works and position of these functional groups provides the classification for these chapters. The strategy chapters cover questions of selectivity, protection, organ works and stereochemistry, organ works and develop more advanced strategic thinking via reagents specially designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery organ works and flavouring compounds, dyestuffs, monomers, organ works and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given, organ works and further examples can be found in the accompanying workbook which also gives many problems organ works and solutions classified in the same way as the main text. The book will also assist more experienced chemists who feel they are out of touch with present day thinking on the subject. Workbook for Organic Synthesis: The Disconnection Approach The workbook which supports this text provides an extra selection of examples. Each example is analysed in the same way as those in the main text with disconnections followed by synthesis,allowing the student to explore a wider range of types of target molecule organ works and synthetic method. The main function of the workbook is, however, to provide a graded series of problems which extend the students experience of the types of molecules being synthesised by organic chemists.
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